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1A) However, when assessing individual protein differences where a specific protein signal had to be present in at least 75% of the participants, we showed that 28 proteins were significantly increased, and 5 proteins significantly reduced in children affected with konzo versus unrelated/unaffected individuals (q 0.5) (Fig

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Redox homeostasis and antioxidant signaling: A metabolic interface between stress perception and physiological responses

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These changes tend to reflect shifts in mechanical demand rather than changes to joint structure

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Methylcobalamin (mB12)/low-dose folinic acid (LDFA) This was a prospective 12-week open-label outpatient treatment trial of subcutaneously injected methylcobalamin (mB12

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Onset: typically 2 to 4 months after starting treatment or a dose increase

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